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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC2H1
All Species:
19.7
Human Site:
S519
Identified Species:
43.33
UniProt:
Q8NCM8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCM8
NP_001073932
4307
492594
S519
G
F
R
C
F
H
Q
S
A
K
D
L
L
D
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536596
4306
491933
S519
G
F
R
S
F
H
R
S
A
E
D
L
L
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q45VK7
4306
492321
S519
G
F
R
S
F
H
R
S
A
E
D
L
L
D
Q
Rat
Rattus norvegicus
Q9JJ79
4306
492200
S519
G
F
R
S
F
H
R
S
A
E
D
L
L
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509757
4391
500194
S610
G
F
R
S
F
R
R
S
A
D
D
L
L
E
Q
Chicken
Gallus gallus
XP_417173
4301
491979
S517
G
F
Q
T
F
H
R
S
A
G
S
F
L
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37276
4639
530166
I689
S
F
R
A
K
L
S
I
S
D
V
F
H
E
W
Honey Bee
Apis mellifera
XP_395108
4023
452032
P493
T
I
G
D
R
M
V
P
S
Q
R
P
L
M
L
Nematode Worm
Caenorhab. elegans
Q19542
4171
473799
W498
E
K
E
C
F
D
D
W
C
R
E
T
V
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36022
4092
471329
K504
N
M
L
D
L
E
K
K
L
Q
N
T
L
A
S
Red Bread Mold
Neurospora crassa
P45443
4367
495560
K706
A
L
H
T
E
G
Q
K
L
Q
N
E
S
D
L
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.5
N.A.
93.3
93
N.A.
85.8
79.7
N.A.
N.A.
N.A.
26.4
30.3
40.7
N.A.
Protein Similarity:
100
N.A.
N.A.
96.5
N.A.
97.1
97
N.A.
91.8
89.4
N.A.
N.A.
N.A.
47.8
52.5
61.2
N.A.
P-Site Identity:
100
N.A.
N.A.
80
N.A.
80
80
N.A.
66.6
53.3
N.A.
N.A.
N.A.
13.3
6.6
13.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
80
73.3
N.A.
N.A.
N.A.
26.6
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.8
27.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
48.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
55
0
0
0
0
10
0
% A
% Cys:
0
0
0
19
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
10
10
0
0
19
46
0
0
46
0
% D
% Glu:
10
0
10
0
10
10
0
0
0
28
10
10
0
28
0
% E
% Phe:
0
64
0
0
64
0
0
0
0
0
0
19
0
0
0
% F
% Gly:
55
0
10
0
0
10
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
10
0
0
46
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
10
0
10
19
0
10
0
0
0
0
0
% K
% Leu:
0
10
10
0
10
10
0
0
19
0
0
46
73
0
28
% L
% Met:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
10
0
0
0
19
0
0
28
0
0
0
0
55
% Q
% Arg:
0
0
55
0
10
10
46
0
0
10
10
0
0
0
0
% R
% Ser:
10
0
0
37
0
0
10
55
19
0
10
0
10
0
10
% S
% Thr:
10
0
0
19
0
0
0
0
0
0
0
19
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _